Categories Biological sciencesMaterial ScienceNanomaterialsTechnology

Advanced Surfaces for Stem Cell Research (Advanced Materials Book Series)

Advanced Surfaces for Stem Cell ResearchAshutosh Tiwari, Bora Garipcan, Lokman Uzun

Hardcover: 480 pages    Publisher: WILEY-Scrivener,USA

Language: English         ISBN: 978-1-119-24250-5

 

 

 

From the Editor-

Stem cells have attracted much attention in regenerative medicine and tissue engineering fields for taking important roles in the treatment of several diseases due to their unique properties such as the capability of self-renewal and differentiation into specific cell types. New research and therapies in these fields are mainly focused on a better understanding of the natural mechanisms of stem cells and the control and regulation of their behavior in vivo or in vitro conditions. Since natural and/or synthetic surface is an important physical structure for the most of the cells, the effect of surface properties such as chemistry, charge, energy, hydropathy, pattern, topography, and stiffness with or without differentiation media influence stem cell behavior as well as control and direct stem cell differentiation. Biomaterials that are developed by altering the surface properties are promising challenge for regenerative medicine and tissue engineering fields, drug investigation/toxicity studies and stem cell based therapies.

The book titled as “Advanced Surfaces in Stem Cell Research” from Advanced Materials outlines first the importance of Extra Cellular Matrix (ECM), which is a natural surface for most of cells in the first chapter of titled as “Extracellular matrix proteins for stem cell fate”. From Chapters 2 to 7, the influence of biological, chemical, mechanical, and physical properties on stem cell behavior and fate were discussed. In Chapter 2, “Mechanical And Physical Properties of Matrix Microenvironment As Stem Cell Fate Regulator” were reviewed followed by “The Effect of Mechanotransduction On Stem Cell Behavior” at Chapter 3.  In Chapter 4 Stem cell modulation on bioactive surfaces were disputed.  Since micro and nano-scale structure and surfaces have an influence on stem cell behavior and fate these properties were discussed at Chapter 5 and Chapter 6 as “Influence of Controlled Micro and Nano-Engineered Surfaces On Stem Cell Fate” and “Recent Advances in Nanostructured Polymeric Surface: Challenges and Frontiers in Stem Cells”. 2D and 3D surface fabrication and modification using different techniques on stem cell fate were deliberated in Chapters 7-10. Laser Surface Modification Techniques and Stem Cells Applications” and  “Plasma polymer deposition: a versatile tool for stem cell researchand were indicated at Chapter 7 and Chapter 8, respectively. In Chapter 9 and Chapter 10, the effect of 3-D structures and dynamic cell environment such as bioreactors on stem cell fate were given in detail as “3D-Printing Approaches for the Treatment of Critical-Sized Bone Defect” and “Application of Bioreactor Concept and Modeling Techniques in Bone Regeneration and Augmentation Treatments”, respectively. Chapter 11 is an important and interesting chapter, which will inform the readers from a different point of view in this field; medical products as “Stem cell-based medicinal products: Regulatory perspectives”.  In Chapter 12, one of the recent stem cell source; Pluripotent Stem Cell cells fate and function were discussed which was titled as “Substrates and Surfaces for Control of Pluripotent Stem Cell Fate and Function”.  Surface engineering applications were discussed in tissue engineering, regenerative medicine and different type of biomaterials in the 13th and  14th chapters of the book as “Silk as a Natural Biopolymer for Tissue Engineering” and “Application of Biopolymer-Based, Surface Modified Devices in Transplant Medicine and Tissue Engineering”. Biomimetic and bioinspired approaches were also indicated to for developing microenvironment of several tissues in the Chapter 15 “Stem Cell Behavior on Microenvironment Mimicked Surfaces“.

We would like to thank the authors that are contributed to the chapters of the book including all scientists contributed into this topic. We do believe and hope this book will be very useful for the biomaterials, tissue engineering, regenerative medicine, stem cell research and material science community.

Description of Book-

Chapter 1

Extracellular matrix proteins for stem cell fate

Betül Çelebi Saltik, Turkey

 Chapter 2

The superficial mechanical and physical properties of matrix microenvironment as stem cell fate regulator

Mohsen Shahrousvand, Iran

Chapter 3

Effects of Mechanotransduction on Stem Cell Behavior

Sedat Odabas, Turkey

Chapter 4

Modulation of Stem Cells Behavior through Bioactive Surfaces

Antonio Salgado, Portugal

Chapter 5

Influence of controlled micro and nanoengineered surfaces on stem cell fate

Anna Lagunas, Spain

Chapter 6

Recent Advances in Nanostructured Polymeric Surface: Challenges and Frontiers in Stem Cells

Ilaria Armentano, Italy

Chapter 7

Laser Surface Modification Techniques and Stem Cells Applications

Cagri Akkan, Turkey

Chapter 8

Plasma polymer deposition: a versatile tool for stem cell research

Melanie macgregor-ramiasa , Australia

Chapter 9

3D-printing approaches for the treatment of critical-sized bone defects

Warren L. Grayson, USA

Chapter 10

Application of bioreactor concept and modeling techniques in bone regeneration and augmentation treatments

Jésica Zuchuat, Argentina

Chapter 11

Stem cell-based medicinal products: Regulatory perspectives

Halil Murat Aydin, Turkey

Chapter 12

Substrates and Surfaces for Control of Pluripotent Stem Cell Fate and Function

Wei Seong Toh, Singapore

Chapter 13

Silk as a Natural Biopolymer for Tissue Engineering

AYSE AK CAN, Turkey

Chapter 14

Application of Biopolymer-Based, Surface Modified Devices in Transplant Medicine and Tissue Engineering

Ashim Malhotra, USA

Chapter 15

Stem Cell Behavior on Microenvironment Mimicked Surfaces

Bora Garipcan, Turkey

vbripressab@gmail.com

Ashutosh Tiwari is Chairman & Managing Director at Institute of Advanced Materials & VBRI Group, Secretary General of the International Association of Advanced Materials and Editor-in-Chief of Advanced Materials Letters. Dr. Tiwari also has several adjuncts and honorary professor titles since 2009. Professor Ashutosh Tiwari has been actively involved in the translational research for building state-of-the-art technological systems to handle key challenges in medical, security, energy supply and environmental issues realized by the integration of artificial intelligence and smart strategies. Currently, Ashutosh works mainly on the technological developments of the range of nanotechnology-enabled new tools, technological breakthroughs, key process, new products designed to transform the energy, IT automation, security, and mass medicine.

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